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Volume 34 , Issue 2
March/April 2014
Pages 179–186

Human Palatal and Tuberosity Mucosa as Donor Sites for Ridge Augmentation

Claudia Dellavia, DDS, PhD/Giano Ricci, DDS/Letizia Pettinari, PhD/Cristina Allievi, DDS, PhD/Fabio Grizzi, PhD/Nicoletta Gagliano, PhD

PMID: 24600654
DOI: 10.11607/prd.1929

Since different clinical outcomes of periodontal bilaminar surgeries using the palate or the maxillary tuberosity as connective tissue (CT) donor sites have been observed, tissues grafted with CT from the palate or the tuberosity 1 year after surgical procedures for ridge augmentation were compared with nongrafted tissues by using morphologic and molecular methods. Collagen content and matrix metalloproteinases 1 and 2 expression were similar in tissues and cultured fibroblasts from the palate and tuberosity, although with interindividual differences. In contrast, differences in collagen cross-linking and maturation in the tuberosity fibroblasts were observed, suggesting a possible role in determining hyperplastic responses in some patients. (Int J Periodontics Restorative Dent 2014;34:179–186. doi: 10.11607/prd.1929)

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